There are already many posts out there like this one, but the more time I spend jumping around and taking new things in from the Internet, the more I run across new and better ways to use my computer. This is a collection of lesser-known applications I use pretty often.
Colibri
This is an application launcher similar to Quicksilver on a Mac. The idea is that you can activate Colibri and start typing the name of the application you want to run, and it returns matching results as you type. I like it because I can remove shortcuts and icons from my desktop, and I can keep my hands on the keyboard.
VirtuaWin
Virtual windows are common on Linux or Mac operating systems. They can be described as a logical way to have 4 windows within one monitor and switch between them. This allows you to organize applications and information into different windows and switch between them. I looked around to see if there was a similar solution for Windows, and I ran into VirtuaWin. After a few minutes to set up navigation short-cuts and other configuration stuff, it seems to work just fine. Unfortunately, you miss out on some of the cool transitions and desktop stuff you would get with the KDE or Gnome desktop managers, it still is a handy tool to have.SpaceTime
Miro
I haven't had the chance to check this one out too much, but it seems pretty cool. It lets you find and download free TV from the Internet. Most of the channels I looked at seemed like obscure channels I've never heard of or had any interest in, but I'm sure it could be fun to use if I give it some time.
OpenPandora
This is one of my favorites. If you are familiar with the Pandora Internet radio service at all, then this is pretty handy. It is a small desktop application that manages your radio without you having to open an Internet browser (granted, you still need an Internet connection). If you like Pandora at all, this is worth checking out.
Google Calendar Sync
This is incredibly useful if you use Microsoft Outlook and have a Google Calendar too. Google Calendar is free to use and you don't need a Google mail account to use it. It's nice because you can access it from anywhere, but you may still want to integrate it into your Outlook application. Google Calendar Sync lets you do just that.
Ok that's it for now. This is by no means an exhaustive list, and all of this stuff was found first in other places, but I thought I'd share with those that know me. I'll be sure to put up more if I find them.
Cheers!